SOD1 and early-onset autosomal dominant Alzheimer disease: In a study of senescence-accelerated prone 8 (SAMP8), mice were fed with a high-fat diet, as a model of Alzheimer’s disease, or with a diet enriched with DHA-PC or DHA-PS, which both increased the activity of antioxidative enzymes GSH-Px and SOD while decreasing malondialdehyde, a marker of lipid peroxidation [63].