We further explore whether visceral fat mass (VFM), thought to be a key marker of glucose homeostasis and lipid metabolism, is a mediator of associations between hypertension and postprandial insulin and triglyceride response in the ZOE UK PREDICT 1 study [9]—a single-arm, randomized cross-over trial of standardized meal interventions designed to quantify and predict individual variations in postprandial responses (NCT03479866). The gene discussed is INS; the disease is Hypertension.