INS and Hypertension: This suggested that VFM was fully mediating the positive association between hypertension and 2-h peak insulin (VAF = 36% (0.02, 0.1) p = 0.002), and partially mediating the positive association between hypertension and 6-h triglyceride peak (variance accounted for (VAF) = 33.8% (0.03, 0.16) p= 0.004) (Figure 3).