This suggestion is supported by: (1) the finding that TCN1 mRNA is overexpressed in cancer tissues compared to adjacent tissues [13]; (2) TCN1 expression is associated with apoptosis and inflammation (i.e., cellular events that are typical to cancer) [53]; and (3) high tissue TCN1 is associated with the presence of invasive tumors, higher tumor markers, metastasis to regional lymph [53], and low response to neoadjuvant chemotherapy [48]. Here, TCN1 is linked to cancer.