AKT1 and pancreatic neoplasm: In addition, the anti-pancreatic ductal carcinoma activity of pectin derived from Lycium ruthenicum Murr (LRP3-S1) was evaluated in AsPC-1, PANC-1, and BxPC-3 pancreatic cancer cell lines, finding it inhibited their development in a dose-dependent manner by altering signaling through the mitogen-activated protein kinase (MAPK) and focal adhesion kinase (FAK)/protein kinase B (AKT)/glycogen synthase kinase-3 (GSK-3) pathways [36].