In the future, the binding information of 2′-FL and VEGFA/VEGFR2 protein will be confirmed, and candidate targets of 2′-FL can be identified by over-expression or small interfering RNA (siRNA); especially, the direct effect of 2′-FL on angiogenesis will be further investigated by experiments, including cell proliferation, cell cycle, and cell migration, as well as tube formation detection of vascular endothelial cells (such as human umbilical vein endothelial cells), which are significant to elucidating further the anti-tumor mechanisms of 2′-FL. The gene discussed is VEGFA; the disease is neoplasm.