STAT3 and lung cancer: Erianin (184) down-regulates the expression of inflammation factors through the regulation of IDO-induced tumor cells angiogenesis mimicry and endothelial cell-dependent angiogenesis by targeting the JAK2/STAT3 pathway and its down-stream genes MMP-2/MMP-9, and thereby inhibits the angiogenesis of lung cancer cells (Figure 3) [153].