In addition, they detected three pathways that affected the composition of the gut microbiota in the three gastrointestinal diseases that were analyzed (CRC, inflammatory bowel disease, and irritable bowel syndrome), namely “Oxidative phosphorylation”, “RAC1 pathway” and “ERBB1 downstream pathway”; and 52 pathways specific to CRC [58]. Here, RAC1 is linked to colorectal carcinoma.