Measurement of IgE to both pholcodine and morphine is useful in the evaluation of allergy to NMBAs according to a retrospective study carried out at the Royal North Sore Hospital Anesthetic Allergy Clinic (Sydney, NSW, Australia) from 2009 to 2019, covering 801 consecutive patients with 255 having skin test results for NMBAs [53]. The gene discussed is IGHE; the disease is allergic disease.