CSF3 and cervical squamous intraepithelial neoplasia: Aapro et al. looked at predictive factors for CIN and FN in patients undergoing prophylactic G-CSF therapy, and assessed their predictive utility at the patient-level (assessment of risk factors, determinants, and predictors before the first cycle of chemotherapy) and cycle-level (reassessment of risk at the beginning of each cycle) [34].