GPT and endothelial dysfunction: Sustained exposure to arsenic results in increased systolic blood pressure, impaired endothelial dysfunction due to impaired NO release, increased levels of total cholesterol (TC), triglycerides (TG), low density lipoprotein (LPL), very low density lipoprotein (VLDL), aspartate aminotransferase (AST), alanine transaminase (ALT), bilirubin, urea, creatinine and decreased levels of HDL that may lead to hypertension [4].