Clinical investigation in surgery or radiotherapy-cured prostate cancer (PCa) patients with increment prostate-specific antigen (PSA) showcased that drinking 8 ounces of pomegranate juice (PJ) (Wonderful variety, 570 mg total polyphenol gallic acid equivalents) daily meaningfully prolongs the PSA doubling time (PSADT) from 15 to 54 months [12]. This evidence concerns the gene KLK3 and Familial prostate cancer.