ICAM1 and ischemia: A significant increase (all p < 0.05) in ICAM-1 concentration in the reperfusion phase was observed with approximately 56% in WKY-CONTROL, 29% in WKY-RF, 20% in WKY-RF+NaHS, 49% in WKY-RF+PAG, 38% in L-NAME-CONTROL, 28% in L-NAME-RF, 18% in L-NAME-RF+NaHS and 34% in L-NAME-RF+PAG when compared to their corresponding groups in the pre-ischemia phase (Figure 7A).