Eugenol at an IC50 value of 1.5 μg/mL is a potent cytotoxic agent which suppressed metastasis and cancer cell migration by downregulating 34.3% matrix metalloproteinase (MMP-9) and 13.7% paxillin mRNA expression levels, respectively, in MCF-7 breast cancer cells [34]. This evidence concerns the gene MMP9 and breast cancer.