These AD-MSC-derived EVs upregulate cyclin D1, D2, A1, and A2 as well as growth factors (VEGF-A, PDGF-A, EGF, and FGF-2); hence, they increase wound epithelialization, collagen synthesis, angiogenesis, and wound contracture [77]. The gene discussed is VEGFA; the disease is Alzheimer disease.