In particular, they found that the PSMA expression in the endothelium of the tumor-associated vasculature is notably higher in PDTC, ATC and iodine-refractory thyroid cancers, concluding that this feature can be considered a biomarker of aggressiveness, in accordance with its important role in tumorigenesis and angiogenesis. This evidence concerns the gene FOLH1 and thyroid gland carcinoma.