Sasikumar et al. described a patient with metastatic CRCC studied with both 18F-FDG and 68Ga-PSMA, reporting significantly higher uptake of mediastinal lymph nodes, suprarenal region, bone metastases and thyroid nodules with 68Ga-PSMA compared to standard 18F-FDG [44]. This evidence concerns the gene FOLH1 and thyroid nodule.