Another study reported an increased Gal-3 expression in the fetal membranes and in the amniotic epithelium in chorioamniotic infection and the preterm premature rupture of the membranes, suggesting the role of Gal-3 in the inflammatory responses in chorioamnionitis and/or in direct interaction with the pathogens [57]. The gene discussed is LGALS3; the disease is chorioamnionitis.