Platelet-derived growth factor-BB (PDGF-BB) is strongly associated with the VEGF pathway and its altered secretion as well as other proangiogenic molecules, such as VEGF, FGF, EGF, TGFβ, angiopoietin in the tumor microenvironment, contributes to the mobilization and differentiation of EPCs and ECs’ proliferation [70]. Here, VEGFA is linked to neoplasm.