This is also a limitation of the study; this limitation can be addressed via a prospective study that examines serial liver function (AST, ALT, albumin, and globulin) and hemostatic parameters (D-dimer, prothrombin time, and thrombocyte level) before the patient is diagnosed with sepsis, at the time of sepsis, and at the time of DIC diagnosis. Here, F2 is linked to Sepsis.