In addition to the case–control analysis of six PDGFRB gene polymorphisms (including rs3756311 and rs3756312 analyzed in the present work), the authors also studied the functional effect of the identified SNPs and haplotypes on promoter activity performing luciferase activity assay in human SH-SY5Y neuroblastoma cells. The gene discussed is PDGFRB; the disease is neuroblastoma.