Five pathways are shared among the CTRL, LC and MPM groups: Defective Polypeptide N-Acetylgalactosaminyltransferase 12 (GALNT3) causes familial hyperphosphatemic tumoral calcinosis (HFTC) (R-HSA-5083625); Defective C1GALT1 Specific Chaperone 1 (C1GALT1C1) causes Tn polyagglutination syndrome (TNPS) (R-HSA-5083632); Defective GALNT12 causes colorectal cancer 1 (CRCS1) (R-HSA-5083636); Dectin-2 family (R-HSA-5621480); and Termination of O-glycan biosynthesis (R-HSA-977068). The gene discussed is C1GALT1C1; the disease is colorectal cancer, susceptibility to, 1.