GPR19 and cancer: Hence many of the most closely-correlated factors associated with GPR19 upregulation are tightly linked with metabolic aging (FASN: [165]; ACLY [166]; NAMPT [167]; CAB39L [168]), mitochondrial and antioxidant activities (H6PD [169]; DIXDC1 [170]), damage-related cell cycle alterations/cancer (FLCN [171]; TES [172]), alterations in unfolded protein management linked to metabolic imbalances (FKBP11 [173]) and oncogenesis (TMTC4 [174]), DNA damage (DDX21 [175], and body weight (STRBP [176].