When we pre-treated C57BL/6J mice with devazepide, a CCK1R inhibitor, at a dose of 1 mg/kg bodyweight, and induced AP using caerulein, serum amylase and lipase activities were abrogated and the addition of TLCS did not further decrease the activity (Figure 7D,E). The gene discussed is CCKAR; the disease is alkaline phosphatase measurement.