In addition, we identified three ceRNA regulatory axes (SNHG1/miR-101-3p/PPFIA4, SNHG1/miR-101-3p/SAP30 and SNHG1/miR-101-3p/TKTL1), which might play an essential role in HCC progression. Here, TKTL1 is linked to hepatocellular carcinoma.