In summary, we constructed a prognostic hypoxia-related ceRNA network for hepatocellular carcinoma via bioinformatics analyses, in which six highly expressed lncRNAs (AC005540.1, AC012146.1, AC073529.1, AC090772.3, AC138150.2, AL390728.6) and one highly expressed mRNA (PPFIA4) were discovered for the first time in this study to be the potential biomarkers of hepatocellular carcinoma. The gene discussed is PPFIA4; the disease is hepatocellular carcinoma.