A recent study examined the genetic impact of CYP2D6 polymorphism on the susceptibility of individuals to develop schizophrenia, and suggested that CYP2D6 variations may alter the structure of the hippocampal white matter region of the brain and the neurotransmission of dopamine; thus, highlighting neuronal connectivity underlying the pathophysiology of schizophrenia [73]. This evidence concerns the gene CYP2D6 and schizophrenia.