CD274 and neoplasm: To determine if peritumoral LECs in vivo depended on IFNγ, we treated WT mice implanted with B16F10 with intraperitoneal injections of anti-IFNγ neutralizing antibody or IgG isotype control and analyzed MHC-II and PD-L1 expression in peritumoral LECs at 14 days post tumor implantation.