BTN3A2 and neoplasm: Strikingly, BTN3A2 was positively correlated with T cell transcription factors, and anti-tumoral mediators, such as TBX21, STAT1, IFNγ, and GZMB, respectively, in triple-negative breast cancer (TNBC), compared with other breast cancer subtypes, which suggests that high expression of BTN3A2 in TNBC patients could significantly increase the number of cytotoxic cells CTLs, Th1, and DC in the tumor microenvironment [47].