CDH1 and chronic kidney disease: We further found that the protein expression of the fibrosis marker α-SMA and epithelial–mesenchymal transition (EMT) activation (i.e., decreased E-cadherin and increased vimentin protein expression) were markedly enhanced in both the left (Figure 7(Ba)) and right (Figure 7(Bb)) kidneys of the adenine-CKD mice, which could be reversed by the LIPUS treatment applied to the left kidneys.