The aberrant expression of lysyl oxidase–like 2 (LOXL2) is associated with fibrotic disorders and metastatic/invasive tumors, and LOXL2 has shown to promote activation of fibroblasts [1,2], proliferation and metastasis/invasion of tumor cells [3,4,5,6], and tumor angiogenesis [7,8]. The gene discussed is LOXL2; the disease is neoplasm.