AKT1 and nasopharyngeal carcinoma: Taken together, we concluded that the enforced expression of huMETCAM/MUC18 suppressed the tumorigenesis of the NPC-TW-01 cells by increasing the apoptosis index (Bax) and by decreasing the anti-apoptosis index (Bcl2), proliferation index (PCNA), signal for the survival pathway (ratio of phospho-AKT/AKT), aerobic glycolysis (LDH-A), and angiogenesis indexes (VEGF), which was confirmed by the results of the vascular density, as shown in Figure 8.