AKT1 and urinary bladder carcinoma: Because a previous study clarified that integrin α3-mediated pathways (e.g., FAK/Src, FAK/PI3K/AKT) are involved in regulation of bladder cancer cell invasion and migration [105], this study by Mani et al. may partly contribute to the antimetastatic effect of the curcumin-light combination on bladder cancer.