WT mice showed mild hepatic steatosis at 24 h after a single dose of TM, as indicated by increased hepatic triglyceride contents, decreased serum triglyceride levels (Figure 6A), enhancement of Oil-Red-O (ORO) staining and its quantification (Figure 6B), whereas HPS-KO mice showed more aggravated hepatic steatosis when exposed to TM (Figure 6A,B). This evidence concerns the gene FGL1 and fatty liver disease.