Nagai et al. also demonstrated that in STZ-induced CD-1 diabetic mice and cytokines-induced cultured endothelial cells, a model of EndMT, Ac-SDKP+ACE inhibitor imidapril decreased fibrosis and EndMT by restoring the level of FGF-induced miR-let-7, which was suppressed in renal fibrosis [71]. Here, ACE is linked to renal fibrosis.