TGFB1 and hypertensive disorder: After induction of hypertension, expression of IL-1β, IL-6, IL-4, TGFβ1, TNFα and GM-CSF significantly increased in the hypertension group compared with the control group, and the level of expression of IL-10, IL-8, IL-12 and IFNg was not detected in the control group (Figure 6A–J).