When the gene expression level of PD-L1 was analyzed, we also observed a positive correlation between CXCL9 expression and CD274 expression (Figure 4C) in our CRC cohort, which was supported by the data of colon cancer (Figure 4D) and rectal cancer cohort from TCGA (Figure 4E). The gene discussed is CXCL9; the disease is colonic neoplasm.