The odds ratios for the distribution of CD4+ T lymphocytes (OR 5.98, 95% CI 0.001–0.0008, p < 0.001), CD8+ T lymphocytes (OR 0.23, 95% CI 0.08–0.59, p < 0.01), CD8CD45RO+ (OR 0.27, 95% CI 0.097–0.695, p < 0.01), and CD4/CD8 ratio (OR 5.69, 95% CI 2.07–17.32, p < 0.001) were strongly associated with endothelial dysfunction risk (Table 9). The gene discussed is CD8A; the disease is endothelial dysfunction.