High levels of CK-MB, cTnT, hs-CRP, and pro-BNP might be explained by the fact that the non-CAS group included patients with cardiovascular diseases which may still cause severe myocardial injuries and inflammation, and a substantial proportion of ASCVD patients had emerging acute myocardial infarction, whereas it was less frequent in non-cardiac death cases. This evidence concerns the gene NPPB and cardiovascular disorder.