TNF and hydrops fetalis: Plasma IL-10 and TNF-α were significantly increased in Pltp-KO mice when compared with WT mice (54.9 ± 2.8 vs. 37.9 ± 3.3 pg/mL for IL-10, 23.7 ± 2.34 vs. 18.1 ± 1.05 pg/mL for TNF-α; p < 0.001 and p < 0.05, respectively), demonstrating an increased response to an inflammatory stimulus in the context of a HF diet (Figure 5A).