Proliferation was increased in HCT116 and SW620 cells while inhibition of cell growth was observed in SW480 cells after bmal1 knockdown [53].A functional relationship between β-catenin and per2 stability in CRC cell lines HCT116 and SW480 implicates a role of the circadian oscillator in β-catenin- mediated effects [54]. Here, BMAL1 is linked to colorectal carcinoma.