In light of studies that have linked SLC15A4/PHT1 to inflammatory diseases [10,16] and IBD [6], here it has been investigated for the first time the expression of SLC15A4/PHT1 protein in colon histological sections of IBD patients with ulcerative colitis (UC), finding its major localization in epithelial cells. The gene discussed is SLC15A4; the disease is ulcerative colitis.