LMNA and Hutchinson-Gilford progeria syndrome: It would be interesting in future works to explore the conditions that could further accelerate aging in 3D organoids in vitro such as the use of factors that inhibit telomerases; the expression of truncated proteins from patients showing accelerated aging, such as progerin from Hutchinson–Gilford progeria syndrome (HGPS); the inhibition of autophagosome function; and the induction of DNA damage [50,51,52].