There has been some primary level studies published -retrospective cohorts- on the expression and possible participation of some oncoproteins and tumor-suppressor proteins in the OLP malignization process, together with other papers evaluating cell proliferative activity, as well as the development of apoptosis in OLP epithelial cells [11,12,13,14,15,16,17,18,19,92,93,94,102]. The gene discussed is TCHP; the disease is oral lichen planus.