CDH1 and neoplasm: The tumor suppressor effects of Merlin are exerted via the promotion of contact inhibition, which it does by facilitating the coupling of the adhesion molecule E-cadherin to EGFR receptors; thus, in addition to maintaining cell–cell junctions, it competes with EGFs for EGFRs, preventing the activation of proliferative pathways linked to these receptors [109,110].