Chemokines and cytokines may also play roles in the antitumor response, essentially CX3CL1, CXCL9 and CXCL10 [213], although other types, such as the chemokine RANTES, have been reported as a possible promoter of OLP malignancy [8,14,15,16,196]. This evidence concerns the gene CXCL9 and oral lichen planus.