Likewise, the amplifications of some chromosomal regions, frequent in oral cancer, such as 3p26/28 and 11q13 [21,68,69,128,191,192,193], are linked to the overregulation of some oncogenes that are located in these areas and which, like CCND1, encode oncoproteins cyclin D1) that stimulate proliferation and generate genomic instability. This evidence concerns the gene CCND1 and lip and oral cavity carcinoma.