INS and neurodegenerative disease: Among the 60 cellular pathways we identified were those involved in the regulation of cell signaling (e.g., insulin signaling), cell adhesion (e.g., focal adhesion), cellular metabolism (e.g., adipogenesis), neurodegenerative diseases (e.g., Alzheimer’s disease), and cellular stress (e.g., oxidative stress and redox pathway), Supplemental Figure S1.