ACTA2 and malignant colon neoplasm: Nevertheless, the ability of cathelicidin to inhibit pathological EMT was reported previously by Cheng et al., who showed that LL-37 inhibited TGFβ-induced gene expression of ACTA2 and VIM as well as protein expression of E-cadherin, Twist1, and Slug in human colon cancer HT-29 cells.