The ensemble of all markers expressed leads us to believe that not only the inflammasome complex is activated, since there is a higher IL-1β expression but also a GSDM-D cleavage that indicates that it is being polymerized into membrane pores and its regulating caspases, that indicate the pyroptosis as being the process for lung injury in COVID-19 [30,54]. This evidence concerns the gene GSDMD and COVID-19.