Firstly, phosphorylation levels of key proteins belonging to different oncogenic signaling pathways and/or associated with PCa development/aggressiveness (i.e., Protein kinase B (AKT), extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), Phosphatase and Tensin Homolog (PTEN) and Androgen Receptor (AR)] were determined by Western blotting after 30 min of SST and CORT exposition (Figure 2A,B). Here, MAPK8 is linked to posterior cortical atrophy.