NPPB and atrial fibrillation: Moreover, B-type natriuretic peptide (BNP) with a cutoff level of 104.5 pg/mL appeared to be the only significant predictor for AFib in a prospective study conducted by Giallafos, in which 18/49 SSc patients with a mean follow-up of 72 ± 24 months developed AFib [34].