During the third trimester, total free (total minus DBP- and albumin-bound) and bioavailable (total minus DBP-bound) maternal 25-hydroxyvitamin D3 (25(OH)D3) correlated with placental 25(OH)D3 in the third trimester, but this trend did not persist in preeclampsia [56,57]. This evidence concerns the gene ALB and preeclampsia.