IL27 and cancer: Some of these included IFN-γ, interferon λ (IFN-λ), IL-12A, CD80, CTLA, checkpoint inhibitor in cancer cells, STAT1, 2, HLA-DQB, MHC II, IL-27, Nuclear receptor coactivator 7 NCOA7, enhances the transcriptional activities of several nuclear receptors; PTGER3, IP10, IL-8, and others as compared to control PBMCs.