We treated GSCs with the NF-κB inhibitor PDTC and the small molecule KJ-Pyr-9, an inhibitor of MYC/NMYC and MAX protein-protein interaction, alone or with TNFα stimulation or co-treatment with standard GBM chemotherapeutic TMZ (Figure 6 and Figure S6). The gene discussed is MYC; the disease is glioblastoma.