Globular Glial Tauopathy. Globular glial tauopathy (GGT) is an occasional type of four-repeat tauopathy characterized by a neuronal accumulation of hyperphosphorylated, truncated, oligomeric, and abnormally conformed 4FR tau in neurons and glial cells (oligodendroglia and astrocyte) with globular inclusions [160]. The gene discussed is MAPT; the disease is tauopathy.